Frontline Combo XL 40-60kg. 4.02ml
Frontline Combo has a distinct insecticidal and acaricidal effect. It is efficient against preimaginal and imaginal phases of evolution of fleas, lices, ticks and louses of cats and dogs. It acts by interacting with ligand-gated chloride channels, in particular those gated by the neurotransmitter gamma-aminobutyric acid (GABA), thereby blocking pre- and post-synaptic transfer of chloride ions across cell membranes. This results in uncontrolled activity of the central nervous system and death of insects or acarines.
(S)-Methoprene is an insect growth regulator (IGR) of the class of compounds known as juvenile hormone analogues that inhibit the development of immature stages of insects. This compound mimics the action of juvenile hormone and causes impaired development and death of the developing stages of fleas.